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Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma
To understand the relationships between the non-GCIMP glioblastoma (GBM) subgroups, we performed mathematical modeling to predict the temporal sequence of driver events during tumorigenesis. The most common order of evolutionary events is 1) chromosome (chr) 7 gain and chr10 loss, followed by 2) CDK...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143139/ https://ncbi.nlm.nih.gov/pubmed/25117714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.06.005 |
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