Two cystic fibrosis transmembrane conductance regulator mutations have different effects on both pulmonary phenotype and regulation of outwardly rectified chloride currents.

Cystic fibrosis (CF), a disorder of electrolyte transport manifest in the lungs, pancreas, sweat duct, and vas deferens, is caused by mutations in the CF transmembrane conductance regulator (CFTR). The CFTR protein has been shown to function as a cAMP-activated chloride channel and also regulates a...

Full description

Saved in:
Bibliographic Details
Main Authors: Fulmer, S B, Schwiebert, E M, Morales, M M, Guggino, W B, Cutting, G R
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC41423/
https://ncbi.nlm.nih.gov/pubmed/7542778
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items