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Dynamical Phase Transitions Reveal Amyloid-like States on Protein Folding Landscapes
Developing an understanding of protein misfolding processes presents a crucial challenge for unlocking the mysteries of human disease. In this article, we present our observations of β-sheet-rich misfolded states on a number of protein dynamical landscapes investigated through molecular dynamics sim...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142240/ https://ncbi.nlm.nih.gov/pubmed/25140433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.046 |
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