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Computational Investigation of Cholesterol Binding Sites on Mitochondrial VDAC
[Image: see text] The mitochondrial voltage-dependent anion channel (VDAC) allows passage of ions and metabolites across the mitochondrial outer membrane. Cholesterol binds mammalian VDAC, and we investigated the effects of binding to human VDAC1 with atomistic molecular dynamics simulations that to...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2014
|
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141696/ https://ncbi.nlm.nih.gov/pubmed/25080204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp504516a |
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