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Changes of activity and isoforms of alkaline sphingomyelinase (nucleotide pyrophosphatase phosphodiesterase 7) in bile from patients undergoing endoscopic retrograde cholangiopancreatography

BACKGROUND: Alkaline sphingomyelinase (NPP7) is an ecto-enzyme expressed in intestinal mucosa, which hydrolyses sphingomyelin (SM) to ceramide and inactivates platelet activating factor. It is also expressed in human liver and released in the bile. The enzyme may have anti-tumour and anti-inflammato...

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Detalhes bibliográficos
Main Authors: Duan, Rui-Dong, Hindorf, Ulf, Cheng, Yajun, Bergenzaun, Per, Hall, Mats, Hertervig, Erik, Nilsson, Åke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141583/
https://ncbi.nlm.nih.gov/pubmed/25100243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-14-138
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