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Identification of aberrant forms of alkaline sphingomyelinase (NPP7) associated with human liver tumorigenesis
Alkaline sphingomyelinase (alk-SMase) is expressed in the intestine and human liver. It may inhibit colonic tumorigenesis, and loss of function mutations have been identified in human colon cancer. The present study investigates its expression in human liver cancer. In HepG2 liver cancer cells, RT–P...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2360232/ https://ncbi.nlm.nih.gov/pubmed/17923876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604013 |
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