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Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis

Intestinal alk-SMase (alkaline sphingomyelinase) is an ectoenzyme related to the NPP (nucleotide phosphodiesterase) family. It has five potential N-glycosylation sites and predicated transmembrane domains at both the N- and C-termini. The amino acid residues forming the two metal-binding sites in NP...

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Bibliografiske detaljer
Main Authors: Wu, Jun, Hansen, Gert H., Nilsson, Åke, Duan, Rui-Dong
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134777/
https://ncbi.nlm.nih.gov/pubmed/15458386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041455
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