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Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis
Intestinal alk-SMase (alkaline sphingomyelinase) is an ectoenzyme related to the NPP (nucleotide phosphodiesterase) family. It has five potential N-glycosylation sites and predicated transmembrane domains at both the N- and C-termini. The amino acid residues forming the two metal-binding sites in NP...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Portland Press Ltd.
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134777/ https://ncbi.nlm.nih.gov/pubmed/15458386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041455 |
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