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Changes of activity and isoforms of alkaline sphingomyelinase (nucleotide pyrophosphatase phosphodiesterase 7) in bile from patients undergoing endoscopic retrograde cholangiopancreatography

BACKGROUND: Alkaline sphingomyelinase (NPP7) is an ecto-enzyme expressed in intestinal mucosa, which hydrolyses sphingomyelin (SM) to ceramide and inactivates platelet activating factor. It is also expressed in human liver and released in the bile. The enzyme may have anti-tumour and anti-inflammato...

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Autors principals: Duan, Rui-Dong, Hindorf, Ulf, Cheng, Yajun, Bergenzaun, Per, Hall, Mats, Hertervig, Erik, Nilsson, Åke
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141583/
https://ncbi.nlm.nih.gov/pubmed/25100243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-14-138
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