Identification of aberrant forms of alkaline sphingomyelinase (NPP7) associated with human liver tumorigenesis

Alkaline sphingomyelinase (alk-SMase) is expressed in the intestine and human liver. It may inhibit colonic tumorigenesis, and loss of function mutations have been identified in human colon cancer. The present study investigates its expression in human liver cancer. In HepG2 liver cancer cells, RT–P...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cheng, Y, Wu, J, Hertervig, E, Lindgren, S, Duan, D, Nilsson, Å, Duan, R-D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2007
Aiheet:
Genetics and Genomics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360232/
https://ncbi.nlm.nih.gov/pubmed/17923876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604013
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