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Targeting B-cell germlines and focusing affinity maturation: the next hurdles in HIV-1-vaccine development?
Vaccines that protect against viral infection usually elicit neutralizing antibodies, but HIV-1 vaccine candidates have failed to induce broad and potent such responses. Broadly active neutralizing antibodies (bNAbs) do, however, slowly emerge in a minority of HIV-1-infected subjects; and passive im...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141483/ https://ncbi.nlm.nih.gov/pubmed/24606603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14760584.2014.894469 |
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