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Allosteric Modulation of M(1) Muscarinic Acetylcholine Receptor Internalization and Subcellular Trafficking
Allosteric modulators are an attractive approach to achieve receptor subtype-selective targeting of G protein-coupled receptors. Benzyl quinolone carboxylic acid (BQCA) is an unprecedented example of a highly selective positive allosteric modulator of the M(1) muscarinic acetylcholine receptor (mACh...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140939/ https://ncbi.nlm.nih.gov/pubmed/24753247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536672 |
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