Hyperglycemia Promotes K-Ras-Induced Lung Tumorigenesis through BASCs Amplification

Oncogenic K-Ras represents the most common molecular change in human lung adenocarcinomas, the major histologic subtype of non–small cell lung cancer (NSCLC). The presence of K-Ras mutation is associated with a poor prognosis, but no effective treatment strategies are available for K-Ras -mutant NSC...

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Bibliographic Details
Main Authors: Micucci, Carla, Orciari, Silvia, Catalano, Alfonso
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140809/
https://ncbi.nlm.nih.gov/pubmed/25144301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105550
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