Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis

Somatic activation of Ras occurs frequently in human cancers, including one-third of lung cancers. Activating Ras mutations also occur in the germline, leading to complex developmental syndromes. The precise mechanism by which Ras activation results in human disease is uncertain. Here we describe th...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Shaw, Alice T., Meissner, Alexander, Dowdle, James A., Crowley, Denise, Magendantz, Margaret, Ouyang, Chensi, Parisi, Tiziana, Rajagopal, Jayaraj, Blank, Leah J., Bronson, Roderick T., Stone, James R., Tuveson, David A., Jaenisch, Rudolf, Jacks, Tyler
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2007
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820943/
https://ncbi.nlm.nih.gov/pubmed/17369402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1526207
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