HIF2α is involved in the expansion of CXCR4-positive cancer stem-like cells in renal cell carcinoma

BACKGROUND: Hypoxia and the subsequent activation of hypoxia-inducible factor-2α (HIF2α) contribute to the progression of a variety of cancers. However, their role in the generation of renal cell carcinoma-derived stem cells has not been fully addressed. METHODS: A sphere formation assay, cell proli...

Full description

Saved in:
Bibliographic Details
Published in:Br J Cancer
Main Authors: Micucci, Carla, Matacchione, Giulia, Valli, Debora, Orciari, Silvia, Catalano, Alfonso
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
Subjects:
Molecular Diagnostics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647880/
https://ncbi.nlm.nih.gov/pubmed/26439684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.338
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items