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Hyperglycemia Promotes K-Ras-Induced Lung Tumorigenesis through BASCs Amplification
Oncogenic K-Ras represents the most common molecular change in human lung adenocarcinomas, the major histologic subtype of non–small cell lung cancer (NSCLC). The presence of K-Ras mutation is associated with a poor prognosis, but no effective treatment strategies are available for K-Ras -mutant NSC...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140809/ https://ncbi.nlm.nih.gov/pubmed/25144301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105550 |
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