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Loss of N-terminal Acetylation Suppresses A Prion Phenotype By Modulating Global Protein Folding

N-terminal acetylation is among the most ubiquitous of protein modifications in eukaryotes. While loss of N-terminal acetylation is associated with many abnormalities, the molecular basis of these effects is known for only a few cases, where acetylation of single factors has been linked to binding a...

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Detalhes bibliográficos
Main Authors: Holmes, William M., Mannakee, Brian K., Gutenkunst, Ryan N., Serio, Tricia R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140192/
https://ncbi.nlm.nih.gov/pubmed/25023910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5383
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