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Selection on Network Dynamics Drives Differential Rates of Protein Domain Evolution

The long-held principle that functionally important proteins evolve slowly has recently been challenged by studies in mice and yeast showing that the severity of a protein knockout only weakly predicts that protein’s rate of evolution. However, the relevance of these studies to evolutionary changes...

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Publicat a:PLoS Genet
Autors principals: Mannakee, Brian K., Gutenkunst, Ryan N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933380/
https://ncbi.nlm.nih.gov/pubmed/27380265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006132
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