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DNA Break Mapping Reveals Topoisomerase II Activity Genome-Wide
Genomic DNA is under constant assault by endogenous and exogenous DNA damaging agents. DNA breakage can represent a major threat to genome integrity but can also be necessary for genome function. Here we present approaches to map DNA double-strand breaks (DSBs) and single-strand breaks (SSBs) at the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139894/ https://ncbi.nlm.nih.gov/pubmed/25056547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150713111 |
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