DNA Break Mapping Reveals Topoisomerase II Activity Genome-Wide

Genomic DNA is under constant assault by endogenous and exogenous DNA damaging agents. DNA breakage can represent a major threat to genome integrity but can also be necessary for genome function. Here we present approaches to map DNA double-strand breaks (DSBs) and single-strand breaks (SSBs) at the...

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Bibliographic Details
Main Authors: Baranello, Laura, Kouzine, Fedor, Wojtowicz, Damian, Cui, Kairong, Przytycka, Teresa M., Zhao, Keji, Levens, David
Format: Artigo
Language:Inglês
Published: MDPI 2014
Subjects:
Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139894/
https://ncbi.nlm.nih.gov/pubmed/25056547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150713111
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