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Mapping DNA Breaks by Next-Generation Sequencing
Here, we present two approaches to map DNA double-strand breaks (DSBs) and single-strand breaks (SSBs) in the genome of human cells. We named these methods respectively DSB-Seq and SSB-Seq. We tested the DSB and SSB-Seq in HCT1116, human colon cancer cells, and validated the results using the topois...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8057127/ https://ncbi.nlm.nih.gov/pubmed/29043624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7306-4_13 |
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