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Mapping DNA Breaks by Next-Generation Sequencing
Here, we present two approaches to map DNA double-strand breaks (DSBs) and single-strand breaks (SSBs) in the genome of human cells. We named these methods respectively DSB-Seq and SSB-Seq. We tested the DSB and SSB-Seq in HCT1116, human colon cancer cells, and validated the results using the topois...
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| 發表在: | Methods Mol Biol |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8057127/ https://ncbi.nlm.nih.gov/pubmed/29043624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7306-4_13 |
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