Caricamento...
Rhes Suppression Enhances Disease Phenotypes in Huntington’s Disease Mice
In Huntington’s disease (HD) mutant HTT is ubiquitously expressed yet the striatum undergoes profound early degeneration. Cell culture studies suggest that a striatal-enriched protein, Rhes, may account for this vulnerability. We investigated the therapeutic potential of silencing Rhes in vivo using...
Salvato in:
| Autori principali: | , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139702/ https://ncbi.nlm.nih.gov/pubmed/25062765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-140094 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|