Evidence of Contribution of iPLA(2)β-Mediated Events During Islet β-Cell Apoptosis Due to Proinflammatory Cytokines Suggests a Role for iPLA(2)β in T1D Development

Type 1 diabetes (T1D) results from autoimmune destruction of islet β-cells, but the underlying mechanisms that contribute to this process are incompletely understood, especially the role of lipid signals generated by β-cells. Proinflammatory cytokines induce ER stress in β-cells and we previously fo...

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Hlavní autoři: Lei, Xiaoyong, Bone, Robert N., Ali, Tomader, Zhang, Sheng, Bohrer, Alan, Tse, Hubert M., Bidasee, Keshore R., Ramanadham, Sasanka
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2014
Témata:
Diabetes-Insulin-Glucagon-Gastrointestinal
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138580/
https://ncbi.nlm.nih.gov/pubmed/25004092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2134
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