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Biochemical and Cell Biological Properties of the Human Prohormone Convertase 1/3 Ser357Gly Mutation: A PC1/3 Hypermorph

Satiety and appetite signaling are accomplished by circulating peptide hormones. These peptide hormones require processing from larger precursors to become bioactive, often by the proprotein convertase 1/3 (PC1/3). Several subcellular maturation steps are necessary for PC1/3 to achieve its optimal e...

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Autors principals: Blanco, Elias H., Peinado, Juan R., Martín, Martín G., Lindberg, Iris
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138575/
https://ncbi.nlm.nih.gov/pubmed/24932808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2151
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