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Mutational analysis of predicted interactions between the catalytic and P domains of prohormone convertase 3 (PC3/PC1)
The subtilisin-like prohormone convertases (PCs) contain an essential downstream domain (P domain), which has been predicted to have a β-barrel structure that interacts with and stabilizes the catalytic domain (CAT). To assess possible sites of hydrophobic interaction, a series of mutant PC3–enhance...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156251/ https://ncbi.nlm.nih.gov/pubmed/12721373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0631617100 |
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