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Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics

Neuropeptides are produced from larger precursors by limited proteolysis, first by endopeptidases and then by carboxypeptidases. Major endopeptidases required for these cleavages include prohormone convertase (PC) 1/3 and PC2. In the present study, quantitative peptidomics analysis was used to chara...

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Main Authors: Wardman, Jonathan H., Zhang, Xin, Gagnon, Sandra, Castro, Leandro M., Zhu, Xiaorong, Steiner, Donald F., Day, Robert, Fricker, Lloyd D.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897930/
https://ncbi.nlm.nih.gov/pubmed/20412386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06760.x
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