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Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics

Neuropeptides are produced from larger precursors by limited proteolysis, first by endopeptidases and then by carboxypeptidases. Major endopeptidases required for these cleavages include prohormone convertase (PC) 1/3 and PC2. In the present study, quantitative peptidomics analysis was used to chara...

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Detalhes bibliográficos
Main Authors: Wardman, Jonathan H., Zhang, Xin, Gagnon, Sandra, Castro, Leandro M., Zhu, Xiaorong, Steiner, Donald F., Day, Robert, Fricker, Lloyd D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897930/
https://ncbi.nlm.nih.gov/pubmed/20412386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06760.x
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