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Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics

Neuropeptides are produced from larger precursors by limited proteolysis, first by endopeptidases and then by carboxypeptidases. Major endopeptidases required for these cleavages include prohormone convertase (PC) 1/3 and PC2. In the present study, quantitative peptidomics analysis was used to chara...

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Bibliographische Detailangaben
Hauptverfasser: Wardman, Jonathan H., Zhang, Xin, Gagnon, Sandra, Castro, Leandro M., Zhu, Xiaorong, Steiner, Donald F., Day, Robert, Fricker, Lloyd D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897930/
https://ncbi.nlm.nih.gov/pubmed/20412386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06760.x
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