The transmembrane domain of the prohormone convertase PC3: A key motif for targeting to the regulated secretory pathway

The biosynthesis of hormones and neuropeptides involves post-translational cleavage of precursors at basic amino acids by prohormone convertases (PCs) predominantly in secretory granules that bud from the trans-Golgi Network. This study reports that the amino acid sequence of PC3 (aa617–638), previo...

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Bibliographic Details
Main Authors: Lou, Hong, Smith, Angela M., Coates, Leigh C., Cawley, Niamh X., Peng Loh, Y., Birch, Nigel P.
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892588/
https://ncbi.nlm.nih.gov/pubmed/17240044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2006.11.011
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