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Pat1 contributes to the RNA binding activity of the Lsm1-7–Pat1 complex
A major mRNA decay pathway in eukaryotes is initiated by deadenylation followed by decapping of the oligoadenylated mRNAs and subsequent 5′-to-3′ exonucleolytic degradation of the capless mRNA. In this pathway, decapping is a rate-limiting step that requires the hetero-octameric Lsm1-7–Pat1 complex...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138329/ https://ncbi.nlm.nih.gov/pubmed/25035297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.045252.114 |
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