Optimization and Validation of a Neutralizing Antibody Assay for HIV-1 in A3R5 Cells

A3R5 is a human CD4(+) lymphoblastoid cell line that was engineered to express CCR5 and is useful for the detection of weak neutralizing antibody responses against tier 2 strains of HIV-1. Here we describe the optimization and validation of the HIV-1 neutralizing antibody assay that utilizes A3R5 ce...

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Hauptverfasser: Sarzotti-Kelsoe, Marcella, Daniell, Xiaoju, Todd, Christopher A., Bilska, Miroslawa, Martelli, Amanda, LaBranche, Celia, Perez, Lautaro G., Ochsenbauer, Christina, Kappes, John C., Rountree, Wes, Denny, Thomas N., Montefiori, David C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138262/
https://ncbi.nlm.nih.gov/pubmed/24607608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.02.013
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