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Optimization and Validation of a Neutralizing Antibody Assay for HIV-1 in A3R5 Cells
A3R5 is a human CD4(+) lymphoblastoid cell line that was engineered to express CCR5 and is useful for the detection of weak neutralizing antibody responses against tier 2 strains of HIV-1. Here we describe the optimization and validation of the HIV-1 neutralizing antibody assay that utilizes A3R5 ce...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138262/ https://ncbi.nlm.nih.gov/pubmed/24607608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.02.013 |
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