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Enhanced Cross-Presentation and Improved CD8(+) T Cell Responses after Mannosylation of Synthetic Long Peptides in Mice
The use of synthetic long peptides (SLP) has been proven to be a promising approach to induce adaptive immune responses in vaccination strategies. Here, we analyzed whether the efficiency to activate cytotoxic T cells by SLP-based vaccinations can be increased by conjugating SLPs to mannose residues...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138033/ https://ncbi.nlm.nih.gov/pubmed/25137039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103755 |
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