A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control

The combination of immune-stimulating strategies has the potency to improve immunotherapy of cancer. Vaccination against neoepitopes derived from patient tumor material can generate tumor-specific T cell immunity, which could reinforce the efficacy of checkpoint inhibitor therapies such as anti-PD-1...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Tondini, Elena, Arakelian, Tsolere, Oosterhuis, Koen, Camps, Marcel, van Duikeren, Suzanne, Han, Wanda, Arens, Ramon, Zondag, Gerben, van Bergen, Jeroen, Ossendorp, Ferry
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791440/
https://ncbi.nlm.nih.gov/pubmed/31646082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1652539
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