Combination of chemotherapy and PD-1 blockade induces T cell responses to tumor non-mutated neoantigens

Here, we developed an unbiased, functional target-discovery platform to identify immunogenic proteins from primary non-small cell lung cancer (NSCLC) cells that had been induced to apoptosis by cisplatin (CDDP) treatment in vitro, as compared with their live counterparts. Among the multitude of prot...

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Publicado no:Commun Biol
Main Authors: Grimaldi, Alessio, Cammarata, Ilenia, Martire, Carmela, Focaccetti, Chiara, Piconese, Silvia, Buccilli, Marta, Mancone, Carmine, Buzzacchino, Federica, Berrios, Julio Rodrigo Giron, D’Alessandris, Nicoletta, Tomao, Silverio, Giangaspero, Felice, Paroli, Marino, Caccavale, Rosalba, Spinelli, Gian Paolo, Girelli, Gabriella, Peruzzi, Giovanna, Nisticò, Paola, Spada, Sheila, Panetta, Mariangela, Letizia Cecere, Fabiana, Visca, Paolo, Facciolo, Francesco, Longo, Flavia, Barnaba, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042341/
https://ncbi.nlm.nih.gov/pubmed/32099064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0811-x
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