Enhanced Cross-Presentation and Improved CD8(+) T Cell Responses after Mannosylation of Synthetic Long Peptides in Mice

The use of synthetic long peptides (SLP) has been proven to be a promising approach to induce adaptive immune responses in vaccination strategies. Here, we analyzed whether the efficiency to activate cytotoxic T cells by SLP-based vaccinations can be increased by conjugating SLPs to mannose residues...

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Autores principales: Rauen, Judith, Kreer, Christoph, Paillard, Arlette, van Duikeren, Suzanne, Benckhuijsen, Willemien E., Camps, Marcel G., Valentijn, A. Rob P. M., Ossendorp, Ferry, Drijfhout, Jan W., Arens, Ramon, Burgdorf, Sven
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138033/
https://ncbi.nlm.nih.gov/pubmed/25137039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103755
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