Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection

Selective histone deacetylase (HDAC) inhibitors have emerged as a potential anti-latency therapy for persistent human immunodeficiency virus type 1 (HIV-1) infection. We utilized a combination of small molecule inhibitors and short hairpin (sh)RNA-mediated gene knockdown strategies to delineate the...

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Hauptverfasser: Barton, Kirston M., Archin, Nancie M., Keedy, Kara S., Espeseth, Amy S., Zhang, Yan-ling, Gale, Jennifer, Wagner, Florence F., Holson, Edward B., Margolis, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138023/
https://ncbi.nlm.nih.gov/pubmed/25136952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102684
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