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Relationship of CYP3A5 genotype and ABCB1 diplotype to tacrolimus disposition in Brazilian kidney transplant patients

AIMS: Tacrolimus (TAC) is one of the most successful immunosuppressive drugs in transplantation. Its pharmacokinetics (PK) and pharmacogenetics (PG) have been extensively studied, with many studies showing the influence of CYP3A5 on TAC metabolism and bioavailability. However, data concerning the fu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cusinato, Diego Alberto C, Lacchini, Riccardo, Romao, Elen A, Moysés-Neto, Miguel, Coelho, Eduardo B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137828/
https://ncbi.nlm.nih.gov/pubmed/24528196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12345
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