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Enantioselective disposition of rabeprazole in relation to CYP2C19 genotypes
AIM: Rabeprazole is metabolized to some extent by CYP2C19. The purpose of this study was to elucidate the pharmacokinetics of each rabeprazole enantiomer in three different CYP2C19 genotype groups. METHODS: Twenty-four healthy subjects, of whom each each were homozygous extensive metabolizers (homEM...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885016/ https://ncbi.nlm.nih.gov/pubmed/16487225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02566.x |
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