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In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles
AIMS: A prospectively enrolled patient cohort was used to assess whether the prediction of CYP2D6 phenotype activity from genotype data could be improved by reclassification of diplotypes or alleles. METHODS: Three hundred and fifty-five patients receiving tamoxifen 20 mg were genotyped for CYP2D6 a...
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| Izdano u: | Br J Clin Pharmacol |
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| Glavni autori: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley & Sons, Ltd
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631184/ https://ncbi.nlm.nih.gov/pubmed/25907378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12665 |
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