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In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles

AIMS: A prospectively enrolled patient cohort was used to assess whether the prediction of CYP2D6 phenotype activity from genotype data could be improved by reclassification of diplotypes or alleles. METHODS: Three hundred and fifty-five patients receiving tamoxifen 20 mg were genotyped for CYP2D6 a...

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書目詳細資料
發表在:Br J Clin Pharmacol
Main Authors: Hertz, Daniel L, Snavely, Anna C, McLeod, Howard L, Walko, Christine M, Ibrahim, Joseph G, Anderson, Steven, Weck, Karen E, Magrinat, Gustav, Olajide, Oludamilola, Moore, Susan, Raab, Rachel, Carrizosa, Daniel R, Corso, Steven, Schwartz, Garry, Peppercorn, Jeffrey M, Evans, James P, Jones, David R, Desta, Zeruesenay, Flockhart, David A, Carey, Lisa A, Irvin, William J
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Ltd 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631184/
https://ncbi.nlm.nih.gov/pubmed/25907378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12665
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