Llwytho...

Mutations in the conserved loop of human U5 snRNA generate use of novel cryptic 5' splice sites in vivo.

We have analyzed base pairing interactions between the U5 snRNA and 5' exon sequences during pre-mRNA splicing in a mammalian in vivo system. We constructed synthetic U5 genes with mutations that alter four bases (C3, U4, U5 and U6) within the invariant 9 nt U5 sequence GCCUUUUAC; transient tra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cortes, J J, Sontheimer, E J, Seiwert, S D, Steitz, J A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1993
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC413781/
https://ncbi.nlm.nih.gov/pubmed/8262061
Tagiau: Ychwanegu Tag
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