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Simultaneous Bayesian Estimation of Alignment and Phylogeny under a Joint Model of Protein Sequence and Structure

For sequences that are highly divergent, there is often insufficient information to infer accurate alignments, and phylogenetic uncertainty may be high. One way to address this issue is to make use of protein structural information, since structures generally diverge more slowly than sequences. In t...

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Détails bibliographiques
Auteurs principaux: Herman, Joseph L., Challis, Christopher J., Novák, Ádám, Hein, Jotun, Schmidler, Scott C.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137710/
https://ncbi.nlm.nih.gov/pubmed/24899668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu184
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