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A Stochastic Evolutionary Model for Protein Structure Alignment and Phylogeny

We present a stochastic process model for the joint evolution of protein primary and tertiary structure, suitable for use in alignment and estimation of phylogeny. Indels arise from a classic Links model, and mutations follow a standard substitution matrix, whereas backbone atoms diffuse in three-di...

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Detalhes bibliográficos
Main Authors: Challis, Christopher J., Schmidler, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697813/
https://ncbi.nlm.nih.gov/pubmed/22723302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mss167
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