BigFoot: Bayesian alignment and phylogenetic footprinting with MCMC

BACKGROUND: We have previously combined statistical alignment and phylogenetic footprinting to detect conserved functional elements without assuming a fixed alignment. Considering a probability-weighted distribution of alignments removes sensitivity to alignment errors, properly accommodates regions...

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Main Authors: Satija, Rahul, Novák, Ádám, Miklós, István, Lyngsø, Rune, Hein, Jotun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744684/
https://ncbi.nlm.nih.gov/pubmed/19715598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-9-217
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