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Efficient representation of uncertainty in multiple sequence alignments using directed acyclic graphs

BACKGROUND: A standard procedure in many areas of bioinformatics is to use a single multiple sequence alignment (MSA) as the basis for various types of analysis. However, downstream results may be highly sensitive to the alignment used, and neglecting the uncertainty in the alignment can lead to sig...

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Publicat a:BMC Bioinformatics
Autors principals: Herman, Joseph L, Novák, Ádám, Lyngsø, Rune, Szabó, Adrienn, Miklós, István, Hein, Jotun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395974/
https://ncbi.nlm.nih.gov/pubmed/25888064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0516-1
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