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Efficient representation of uncertainty in multiple sequence alignments using directed acyclic graphs

BACKGROUND: A standard procedure in many areas of bioinformatics is to use a single multiple sequence alignment (MSA) as the basis for various types of analysis. However, downstream results may be highly sensitive to the alignment used, and neglecting the uncertainty in the alignment can lead to sig...

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Библиографические подробности
Опубликовано в: :BMC Bioinformatics
Главные авторы: Herman, Joseph L, Novák, Ádám, Lyngsø, Rune, Szabó, Adrienn, Miklós, István, Hein, Jotun
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395974/
https://ncbi.nlm.nih.gov/pubmed/25888064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0516-1
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