The Acute Phase of Trypanosoma cruzi Infection Is Attenuated in 5-Lipoxygenase-Deficient Mice

In the present work we examine the contribution of 5-lipoxygenase- (5-LO-) derived lipid mediators to immune responses during the acute phase of Trypanosoma cruzi infection in 5-LO gene knockout (5-LO(−/−)) mice and wild-type (WT) mice. Compared with WT mice, the 5-LO(−/−) mice developed less parasi...

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Hlavní autoři: Canavaci, Adriana M. C., Sorgi, Carlos A., Martins, Vicente P., Morais, Fabiana R., de Sousa, Érika V. G., Trindade, Bruno C., Cunha, Fernando Q., Rossi, Marcos A., Aronoff, David M., Faccioli, Lúcia H., Nomizo, Auro
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137569/
https://ncbi.nlm.nih.gov/pubmed/25165415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/893634
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