The Acute Phase of Trypanosoma cruzi Infection Is Attenuated in 5-Lipoxygenase-Deficient Mice

In the present work we examine the contribution of 5-lipoxygenase- (5-LO-) derived lipid mediators to immune responses during the acute phase of Trypanosoma cruzi infection in 5-LO gene knockout (5-LO(−/−)) mice and wild-type (WT) mice. Compared with WT mice, the 5-LO(−/−) mice developed less parasi...

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Bibliographic Details
Main Authors: Canavaci, Adriana M. C., Sorgi, Carlos A., Martins, Vicente P., Morais, Fabiana R., de Sousa, Érika V. G., Trindade, Bruno C., Cunha, Fernando Q., Rossi, Marcos A., Aronoff, David M., Faccioli, Lúcia H., Nomizo, Auro
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137569/
https://ncbi.nlm.nih.gov/pubmed/25165415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/893634
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