The Acute Phase of Trypanosoma cruzi Infection Is Attenuated in 5-Lipoxygenase-Deficient Mice

In the present work we examine the contribution of 5-lipoxygenase- (5-LO-) derived lipid mediators to immune responses during the acute phase of Trypanosoma cruzi infection in 5-LO gene knockout (5-LO(−/−)) mice and wild-type (WT) mice. Compared with WT mice, the 5-LO(−/−) mice developed less parasi...

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Bibliografske podrobnosti
Main Authors: Canavaci, Adriana M. C., Sorgi, Carlos A., Martins, Vicente P., Morais, Fabiana R., de Sousa, Érika V. G., Trindade, Bruno C., Cunha, Fernando Q., Rossi, Marcos A., Aronoff, David M., Faccioli, Lúcia H., Nomizo, Auro
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137569/
https://ncbi.nlm.nih.gov/pubmed/25165415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/893634
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