The Acute Phase of Trypanosoma cruzi Infection Is Attenuated in 5-Lipoxygenase-Deficient Mice

In the present work we examine the contribution of 5-lipoxygenase- (5-LO-) derived lipid mediators to immune responses during the acute phase of Trypanosoma cruzi infection in 5-LO gene knockout (5-LO(−/−)) mice and wild-type (WT) mice. Compared with WT mice, the 5-LO(−/−) mice developed less parasi...

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Bibliografiska uppgifter
Huvudupphovsmän: Canavaci, Adriana M. C., Sorgi, Carlos A., Martins, Vicente P., Morais, Fabiana R., de Sousa, Érika V. G., Trindade, Bruno C., Cunha, Fernando Q., Rossi, Marcos A., Aronoff, David M., Faccioli, Lúcia H., Nomizo, Auro
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137569/
https://ncbi.nlm.nih.gov/pubmed/25165415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/893634
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