miR-210 promotes IPF fibroblast proliferation in response to hypoxia

Idiopathic pulmonary fibrosis (IPF) is characterized by the relentless spread of fibroblasts from scarred alveoli into adjacent alveolar units, resulting in progressive hypoxia and death by asphyxiation. Although hypoxia is a prominent clinical feature of IPF, the role of hypoxia as a driver of the...

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Autores principales: Bodempudi, Vidya, Hergert, Polla, Smith, Karen, Xia, Hong, Herrera, Jeremy, Peterson, Mark, Khalil, Wajahat, Kahm, Judy, Bitterman, Peter B., Henke, Craig A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137166/
https://ncbi.nlm.nih.gov/pubmed/24951777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00069.2014
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