OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma

BACKGROUND: The successful gene delivery into the brain is a major challenge due to the presence of the blood–brain barrier (BBB). In order to transport plasmid DNA across the BBB and target the brain glioma, the PEGylated liposomes (PLs) modified with OX26 and chlorotoxin (CTX) were developed as a...

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Библиографические подробности
Главные авторы: Yue, Pei-jian, He, Lei, Qiu, Shu-wei, Li, Yi, Liao, Yi-ji, Li, Xiang-pen, Xie, Dan, Peng, Ying
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137094/
https://ncbi.nlm.nih.gov/pubmed/25128329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-191
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