OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma

BACKGROUND: The successful gene delivery into the brain is a major challenge due to the presence of the blood–brain barrier (BBB). In order to transport plasmid DNA across the BBB and target the brain glioma, the PEGylated liposomes (PLs) modified with OX26 and chlorotoxin (CTX) were developed as a...

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Detalhes bibliográficos
Main Authors: Yue, Pei-jian, He, Lei, Qiu, Shu-wei, Li, Yi, Liao, Yi-ji, Li, Xiang-pen, Xie, Dan, Peng, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137094/
https://ncbi.nlm.nih.gov/pubmed/25128329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-191
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