OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma

BACKGROUND: The successful gene delivery into the brain is a major challenge due to the presence of the blood–brain barrier (BBB). In order to transport plasmid DNA across the BBB and target the brain glioma, the PEGylated liposomes (PLs) modified with OX26 and chlorotoxin (CTX) were developed as a...

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Bibliografiske detaljer
Main Authors: Yue, Pei-jian, He, Lei, Qiu, Shu-wei, Li, Yi, Liao, Yi-ji, Li, Xiang-pen, Xie, Dan, Peng, Ying
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137094/
https://ncbi.nlm.nih.gov/pubmed/25128329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-191
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